OECD 471, 473, 476, 487, 490 - Mutagenicity / Genotoxicity Tests in vitro Test Method

in vitro Test - OECD 471, OECD 473, OECD 476, OECD 487, OECD 490 Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com INVITRO-CONNECT GmbH can perform for you a complete set of in vitro tests in our GLP-certified cooperation laboratories, which can when required, be complemented by further well-established in vivo tests. IN VITRO GENOTOXICOLOGY / Mutagenicity Tests in vitro Test Method -------------------------------------------------------------------------------------------- - in vitro gene mutation study in bacteria: Ames Test OECD 471 / OPPTS / ICH - in vitro gene mutation study in mammalian cells: Mouse Lymphoma Assay (MLTK Assay) OECD 490 / OPPTS / ICH - in vitro gene mutation study in mammalian cells: HPRT test / OECD 476 / OPPTS / ICH - Micronucleus Assay in vitro (Human Lymphocytes or V79 cells) / OECD 487 / OPPTS / ICH - Chromosomal aberration Assay in vitro (Human Lymphocytes or V79 cells) / OECD 473 / OPPTS / ICH - Hen’s Egg Test – Induction of Micronuclei (HET-MN) - COMET Assay in different cell types iN VITRO DETECTION OF NON-GENOTOXIC CARCINOGENS - Cell Transformation Assay in Bhas Cells / OECD 231 (draft) IN VIVO GENOTOXICOLOGY / Mutagenicity Tests in vivo Test Method -------------------------------------------------------------------------------------------- INVITRO-CONNECT GmbH also offers further Tests / IN VIVO GENOTOXICOLOGY. - Mammalian Erythrocyte Micronucleus Test / OECD 474 / ISO 10993-3 - Combined Mammalian Erythrocyte Micronucleus Test with concurrent Alkaline Comet Assay in vivo OECD 474 & 489 - In vivo Mammalian Alkaline Comet Assay (several organs on request) / OECD 489 - Unscheduled DNA synthesis (UDS) Test with Mammalian Liver Cells in vivo / OECD 486 - Mammalian Spermatogonial Chromosomal Aberration test / OECD 483 - Mammalian Bone Marrow Chromosomal Aberration test / OECD 475 For more information please contact INVITRO-CONNECT GmbH for assistance in developing specialized protocols for your test materials. INVITRO-CONNECT GmbH: Fast Project Execution: personal - competent - reliable --> contact@invitro-connect.com More than 80 test laboratories - Product safety - Regulatory service - In vitro tests - All OECD tests for pharmaceuticals, chemicals, medical devices and cosmetics - Study monitoring, MSDS etc.